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Ismailoglu I, Chen Q, Popowski M, Yang L, Gross SS, Brivanlou AH. " Huntingtin protein is essential for mitochondrial metabolism, bioenergetics and structure in murine embryonic stem cells." Dev Biol. 2014 Jul 15;391(2):230-40. doi: 10.1016/j.ydbio.2014.04.005. Epub 2014 Apr 26..

Dave B, Granados-Principal S, Zhu R, Benz S, Rabizadeh S, Soon-Shiong P, Yu KD5, Shao Z, Li X, Gilcrease M, Lai Z, Chen Y, Huang TH, Shen H, Liu X, Ferrari M, Zhan M, Wong ST, Kumaraswami M, Mittal V, Chen X, Gross SS, Chang JC. " Targeting RPL39 and MLF2 reduces tumor initiation and metastasis in breast cancer by inhibiting nitric oxide synthase signaling" Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8838-43. doi: 10.1073/pnas.1320769111. Epub 2014 May 29..

Abbott GW, Tai KK, Neverisky DL, Hansler A, Hu Z, Roepke TK, Lerner DJ, Chen Q, Liu L, Zupan B, Toth M, Haynes R, Huang X, Demirbas D, Buccafusca R, Gross SS, Kanda VA, Berry GT. " KCNQ1, KCNE2, and Na+-coupled solute transporters form reciprocally regulating complexes that affect neuronal excitability.." Sci Signal. 2014 Mar 4;7(315):ra22. doi: 10.1126/scisignal.2005025..

Diani-Moore S, Ma Y, Gross SS, Rifkind AB. " Increases in levels of epoxyeicosatrienoic and dihydroxyeicosatrienoic acids (EETs and DHETs) in liver and heart in vivo by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and in hepatic EET:DHET ratios by cotreatment with TCDD and the soluble epoxide hydrolase inhibitor AUDA.." Drug Metab Dispos. 2014 Feb;42(2):294-300. doi: 10.1124/dmd.113.055368. Epub 2013 Dec 5..



Deeb RS, Nuriel T, Cheung C, Summers B, Lamon BD, Gross SS, Hajjar DP. " Characterization of a cellular denitrase activity that reverses nitration of cyclooxygenase." Am J Physiol Heart Circ Physiol. 2013 Sep 1;305(5):H687-98. doi: 10.1152/ajpheart.00876.2012. Epub 2013 Jun 21..

Witherspoon M, Chen Q, Kopelovich L, Gross SS, Lipkin SM. " Unbiased metabolite profiling indicates that a diminished thymidine pool is the underlying mechanism of colon cancer chemoprevention by alpha-difluoromethylornithine." Cancer Discov. 2013 Sep;3(9):1072-81. doi: 10.1158/2159-8290.CD-12-0305. Epub 2013 Jun 14..

Lu C, Kavalier A, Lukyanov E, Gross SS. " S-sulfhydration/desulfhydration and S-nitrosylation/denitrosylation: a common paradigm for gasotransmitter signaling by H2S and NO.." Methods. 2013 Aug 1;62(2):177-81. doi: 10.1016/j.ymeth.2013.05.020. Epub 2013 Jun 27..

Yoon Y, McKenna MC, Rollins DA, Song M, Nuriel T, Gross SS, Xu G, Glatt CE. " Anxiety-associated alternative polyadenylation of the serotonin transporter mRNA confers translational regulation by hnRNPK." Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11624-9. doi: 10.1073/pnas.1301485110. Epub 2013 Jun 24..

Kurland IJ, Accili D, Burant C, Fischer SM, Kahn BB, Newgard CB, Ramagiri S, Ronnett GV, Ryals JA, Sanders M, Shambaugh J, Shockcor J, Gross SS. " Application of combined omics platforms to accelerate biomedical discovery in diabesity." Ann N Y Acad Sci. 2013 May;1287:1-16. doi: 10.1111/nyas.12116. Epub 2013 May 9..

Addabbo F, Chen Q, Patel DP, Rabadi M, Ratliff B, Zhang F, Jasmin JF, Wolin M, Lisanti M, Gross SS, Gross SS, Goligorsky MS. " Glutamine supplementation alleviates vasculopathy and corrects metabolic profile in an in vivo model of endothelial cell dysfunction." PLoS One. 2013 Jun 11;8(6):e65458. doi: 10.1371/journal.pone.0065458. Print 2013...



Moskowitz-Kassai E, Mackelaite L, Chen J, Patel K, Dadhania DM, Gross SS, Chander P, Delaney V, Deng L, Chen L, Cui X, Suthanthiran M, Goligorsky MS. " Excretion of anti-angiogenic proteins in patients with chronic allograft dysfunction." Nephrol Dial Transplant. 2012 Feb;27(2):494-7. doi: 10.1093/ndt/gfr638. Epub 2012 Jan 17..

Chen Q, Park HC, Goligorsky MS, Chander P, Fischer SM, Gross SS. " Untargeted plasma metabolite profiling reveals the broad systemic consequences of xanthine oxidoreductase inactivation in mice." PLoS One. 2012;7(6):e37149. doi: 10.1371/journal.pone.0037149. Epub 2012 Jun 18..



Moulick K, Ahn JH, Zong H, Rodina A, Cerchietti L, Gomes DaGama EM, Caldas-Lopes E, Beebe K, Perna F, Hatzi K, Vu LP, Zhao X, Zatorska D, Taldone T, Smith-Jones P, Alpaugh M, Gross SS, Pillarsetty N, Ku T, Lewis JS, Larson SM, Levine R, Erdjument-Bromage H, Guzman ML, Nimer SD, Melnick A, Neckers L, Chiosis G. " Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90" Nat Chem Biol. 2011 Sep 25;7(11):818-26. doi: 10.1038/nchembio.670..

Nuriel T, Hansler A, Gross SS " Protein nitrotryptophan: formation, significance and identification." J Proteomics. 2011 Oct 19;74(11):2300-12. doi: 10.1016/j.jprot.2011.05.032. Epub 2011 Jun 6..

Diani-Moore S, Ma Y, Labitzke E, Tao H, David Warren J, Anderson J, Chen Q, Gross SS, Rifkind AB "Discovery and biological characterization of 1-(1H-indol-3-yl)-9H-pyrido[3,4-b]indole as an aryl hydrocarbon receptor activator generated by photoactivation of tryptophan by sunlight." Chem Biol Interact. 2011 Sep 5;193(2):119-28. doi: 10.1016/j.cbi.2011.05.010. Epub 2011 Jun 22..

Zhou P, Qian L, Gallo EF, Deeb RS, Anrather J, Gross SS, Iadecola C, "The scavenger receptor CD36 contributes to the neurotoxicity of bone marrow-derived monocytes through peroxynitrite production." Neurobiol Dis. 2011 Jun;42(3):292-9. doi: 10.1016/j.nbd.2011.01.019. Epub 2011 Feb 3..

Higgins C, Gross SS, "The N-terminal peptide of mammalian GTP cyclohydrolase I is an autoinhibitory control element and contributes to binding the allosteric regulatory protein GFRP " J Biol Chem. 2011 Apr 8;286(14):11919-28. doi: 10.1074/jbc.M110.196204. Epub 2010 Dec 16..



Higgins C, Gross SS, "Tetrahydrobiopterin: An Essential Cofactor for Nitric Oxide Synthases and Amino Acid Hydroxylases " Nitric Oxide, Second Edition: Biology and Pathobiology, Edited by Louis J. Ignarro, Second Edition, Pages 169-209.

Deeb R, Nuriel T, Gross SS, " Untargeted Discovery of Nitric Oxide-Modified Proteins. " Nitric Oxide, Second Edition: Biology and Pathobiology, Edited by Louis J. Ignarro, Second Edition, Chapter 10, Pages 327-389.

Crabtree MJ, Smith CL, Lam G, Goligorsky MS, Gross SS, "Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs. superoxide production by eNOS.. " Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1530-40. doi: 10.1152/ajpheart.00823.2007. Epub 2008 Jan 11.

Deeb RS, Cheung C, Nuriel T, Lamon BD, Upmacis RK, Gross SS, Hajjar DP. "Physical evidence for substrate binding in preventing cyclooxygenase inactivation under nitrative stress. " J Am Chem Soc. 2010 Mar 24;132(11):3914-22. doi: 10.1021/ja910578y..



Oh JE, Zupan B, Gross SS Toth M. "Paradoxical anxiogenic response of juvenile mice to fluoxetine." Neuropsychopharmacology. 2009 Sep;34(10):2197-207. doi: 10.1038/npp.2009.47. Epub 2009 May 13..

Caldas-Lopes E, Cerchietti L, Ahn JH, Clement CC, Robles AI, Rodina A, Moulick K, Taldone T, Gozman A, Guo Y, Wu N, de Stanchina E, White J, Gross SS, Ma Y, Varticovski L, Melnick A, Chiosis G. "Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models" Proc Natl Acad Sci U S A. 2009 May 19;106(20):8368-73. doi: 10.1073/pnas.0903392106. Epub 2009 May 5...

Hao G, Wang D, Gu J, Shen Q, Gross SS, Wang Y. "Neutral loss of isocyanic acid in peptide CID spectra: a novel diagnostic marker for mass spectrometric identification of protein citrullination." J Am Soc Mass Spectrom. 2009 Apr;20(4):723-7. doi: 10.1016/j.jasms.2008.12.012. Epub 2008 Dec 30..



O'Riordan E, Orlova TN, Mendelev N, Patschan D, Kemp R, Chander PN, Hu R, Hao G, Gross SS, Iozzo RV, Delaney V, Goligorsky MS. "Urinary proteomic analysis of chronic allograft nephropathy." Proteomics Clin Appl. 2008 Jul;2(7-8):1025-35. doi: 10.1002/prca.200780137.

Aguilar D, Skrabanek L, Gross SS, Oliva B, Campagne F. "Beyond tissue Info: functional prediction using tissue expression profile similarity searches." Nucleic Acids Res. 2008 Jun;36(11):3728-37. doi: 10.1093/nar/gkn233. Epub 2008 May 15..

Crabtree MJ, Smith CL, Lam G, Goligorsky MS, Gross SS. "Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs. superoxide production by eNOS." Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1530-40. doi: 10.1152/ajpheart.00823.2007. Epub 2008 Jan 11..

Deeb RS, Upmacis RK, Lamon BD, Gross SS, Hajjar DP. "Maintaining equilibrium by selective targeting of cyclooxygenase pathways: promising offensives against vascular injury." Hypertension. 2008 Jan;51(1):1-7. Epub 2007 Nov 12.

Nuriel T, Deeb RS, Hajjar DP, Gross SS. "Protein 3-nitrotyrosine in complex biological samples: quantification by high-pressure liquid chromatography/electrochemical detection and emergence of proteomic approaches for unbiased identification of modification sites." Methods Enzymol. 2008;441:1-17.

Crabtree MJ, Smith CL, Lam G, Goligorsky MS, Gross SS.  “Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in no vs. superoxide production by eNOS.” Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1530-40. Epub 2008 Jan 11.



Upmacis RK, Crabtree MJ, Deeb RS, Shen H, Lane PB, Benguigui LE, Maeda N, Hajjar DP, Gross SS.  “Profound biopterin oxidation and protein tyrosine nitration in tissues of ApoE-null mice on an atherogenic diet: contribution of inducible nitric oxide synthase.” Am J Physiol Heart Circ Physiol. 2007 Nov;293(5):H2878-87. Epub 2007 Aug 31.

Derakhshan B, Wille PC, Gross SS.  “Unbiased identification of cysteine S-nitrosylation sites on proteins.” Nat Protoc. 2007;2(7):1685-91.

Derakhshan B, Hao G, Gross SS.  “Balancing reactivity against selectivity: the evolution of protein S-nitrosylation as an effector of cell signaling by nitric oxide.” Cardiovasc Res. 2007 Jul 15;75(2):210-9. Epub 2007 May 3.

Dzavík V, Cotter G, Reynolds HR, Alexander JH, Ramanathan K, Stebbins AL, Hathaway D, Farkouh ME, Ohman EM, Baran DA, Prondzinsky R, Panza JA, Cantor WJ, Vered Z, Buller CE, Kleiman NS, Webb JG, Holmes DR, Parrillo JE, Hazen SL, Gross SS, Harrington RA, Hochman JS; Should we inhibit nitric oxide synthase in cardiogenic shock 2 (SHOCK-2) investigators.  “Effect of nitric oxide synthase inhibition on haemodynamics and outcome of patients with persistent cardiogenic shock complicating acute myocardial infarction: a phase II dose-ranging study.” Eur Heart J. 2007 May;28(9):1109-16. Epub 2007 Apr 25.



Gross SS, Hattori Y. (2005) Room for both tyrosine nitration and cysteine nitrosylation to regulate NFkappaB activity, but perhaps only one modification at a time. Cardiovasc Res. 67(4):747-8.

Hattori Y, Akimoto K, Gross SS, Hattori S, Kasai K. (2005) Angiotensin-II-induced oxidative stress elicits hypoadiponectinaemia in rats. Diabetologia. 48(6):1066-74.

Chander PN, Gealekman O, Brodsky SV, Elitok S, Tojo A, Crabtree M, Gross SS, Goligorsky MS. (2004) Nephropathy in Zucker diabetic fat rat is associated with oxidative and nitrosative stress: prevention by chronic therapy with a peroxynitrite scavenger ebselen. J Am Soc Nephrol. 15(9):2391-403.

Kolinsky MA, Gross SS. (2004) The mechanism of potent GTP cyclohydrolase I inhibition by 2,4-diamino-6-hydroxypyrimidine: requirement of the GTP cyclohydrolase I feedback regulatory protein. J Biol Chem. 279(39):40677-82.

Hattori Y, Kasai K, Gross SS. (2004) NO suppresses while peroxynitrite sustains NF-kappaB: a paradigm to rationalize cytoprotective and cytotoxic actions attributed to NO. Cardiovasc Res. 63(1):31-40.

Hao, G., Xie, L. and Gross, S.S. (2004) S-nitrosylation of argininosuccinate synthetase: a mechanism that evolved to limit NO overproduction. J. Biol. Chem. 279(35):36192-200.

Gao S., Chen J., Brodsky S.V., Huang H., Adler S., Lee J.H., Dhadwal N., Cohen-Gould L., Gross S.S., Goligorsky M.S. (2004) Docking of eNOS to the mitochondrial outer membrane: A pentabasic amino acid sequence in the autoinhibitory domain of eNOS targets a proteinase K-cleavable peptide on the cytoplasmic face of mitochondria. J. Biol. Chem. 279: 1-7.

Brodsky, S., Gaelikman, O., Chen, J., Kohen, A., Zhang, F., Crabtree, M., Gross, S.S., Nasjletti, A. and Goligorsky, M.S. (2004) Premature endothelial cell senescence and vasculaopathy in obesity-induced diabetes are preventable by chronic treatment with the peroxynitrite scavenger ebselen. Circ. Res. 94: 1-8.

Felsen D, Schulsinger D, Gross SS, Kim FY, Marion D, Vaughan ED Jr. (2003) Renal hemodynamic and ureteral pressure changes in response to ureteral obstruction: the role of nitric oxide. J Urol. 169:373-6.

Felsen D, Dardashti K, Ostad M, Lemer ML, Gross SS, Chen J, Vaughan ED Jr, Poppas DP. (2003) Inducible nitric oxide synthase promotes pathophysiological consequences of experimental bladder outlet obstruction. J Urol. 169:1569-72.

Crabtree M, Hao G, Gross SS. (2003) Detection of cysteine S-nitrosylation and tyrosine 3-nitration in kidney proteins. Methods Mol Med. 86:373-84.

Chen J, Brodsky SV, Goligorsky DM, Hampel DJ, Li H, Gross SS, Goligorsky MS. (2002) Glycated collagen I induces premature senescence-like phenotypic changes in endothelial cells. Circ Res. 90(12):1290-8.

Lane, P and Gross, SS (2002) Disabling a C-terminal autoinhibitory control element in endotelial NO synthase by phosphorylation provides a molecular explanation for activation of vascular NOsynthesis by diverse physiological stimuli. J. Biol. Chem. 277:19087-94.

Weissman, BA, Jones, C.L., Liu, Q., Gross SS. (2002)  Activation and inactivation of neuronal nitric oxide synthase: characterization of Ca(2+)-dependent [125I]Calmodulin binding. Eur J Pharmacol. 435: 9-18.

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